GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| UCEC | cis | rs9309473 | 1 | rs7594511 | chr2:73681639 | ALMS1P | chr2:73872046-73912692:+ | 0.47 | 5.57 | 1.11E-7 | Metabolite levels |
| UCEC | cis | rs60843830 | 1 | rs7595075 | chr2:264019 | SH3YL1 | chr2:218138-264810:- | -0.5 | -6.77 | 2.7E-10 | Spherical equivalent (joint main effects and education interaction) |
| UCEC | cis | rs9309473 | 1 | rs7598396 | chr2:73652628 | ALMS1P | chr2:73872046-73912692:+ | 0.47 | 5.57 | 1.14E-7 | Metabolite levels |
| UCEC | cis | rs9309473 | 1 | rs7604682 | chr2:73788026 | ALMS1P | chr2:73872046-73912692:+ | 0.53 | 6.32 | 2.73E-9 | Metabolite levels |
| UCEC | cis | rs60843830 | 1 | rs7605824 | chr2:280819 | SH3YL1 | chr2:218138-264810:- | 0.48 | 6.38 | 1.98E-9 | Spherical equivalent (joint main effects and education interaction) |
| UCEC | cis | rs9309473 | 1 | rs7607014 | chr2:73730174 | ALMS1P | chr2:73872046-73912692:+ | -0.48 | -5.52 | 1.45E-7 | Metabolite levels |
| UCEC | cis | rs10935120 | 1 | rs7611828 | chr3:134250325 | ANAPC13 | chr3:134196547-134204865:- | 0.4 | 4.62 | 8.08E-6 | Height |
| UCEC | cis | rs9815354 | 1 | rs7616844 | chr3:41874343 | ULK4 | chr3:41288091-42003660:- | 0.54 | 6.51 | 1.02E-9 | Diastolic blood pressure |
| UCEC | cis | rs9815354 | 1 | rs7617397 | chr3:41959037 | ULK4 | chr3:41288091-42003660:- | -0.48 | -5.78 | 4.15E-8 | Diastolic blood pressure |
| UCEC | cis | rs9815354 | 1 | rs7622259 | chr3:41881351 | ULK4 | chr3:41288091-42003660:- | 0.52 | 6.33 | 2.61E-9 | Diastolic blood pressure |
| UCEC | cis | rs9815354 | 1 | rs7624372 | chr3:41881107 | ULK4 | chr3:41288091-42003660:- | 0.52 | 6.33 | 2.61E-9 | Diastolic blood pressure |
| UCEC | cis | rs9815354 | 1 | rs7632387 | chr3:41853161 | ULK4 | chr3:41288091-42003660:- | 0.47 | 5.3 | 4.01E-7 | Diastolic blood pressure |
| UCEC | cis | rs10935120 | 1 | rs7637227 | chr3:134244155 | ANAPC13 | chr3:134196547-134204865:- | 0.4 | 4.63 | 7.91E-6 | Height |
| UCEC | cis | rs9815354 | 1 | rs7646144 | chr3:41853125 | ULK4 | chr3:41288091-42003660:- | 0.48 | 5.32 | 3.68E-7 | Diastolic blood pressure |
| UCEC | cis | rs9815354 | 1 | rs76471037 | chr3:41799414 | ULK4 | chr3:41288091-42003660:- | 0.52 | 6.19 | 5.36E-9 | Diastolic blood pressure |